{"id":14242,"date":"2019-09-02T13:17:37","date_gmt":"2019-09-02T13:17:37","guid":{"rendered":"https:\/\/www.healthymale.com\/squad\/?p=14242"},"modified":"2019-09-02T13:17:37","modified_gmt":"2019-09-02T13:17:37","slug":"gout-increases-risk-of-kidney-disease","status":"publish","type":"post","link":"https:\/\/www.healthymale.com\/blog\/gout\/gout-increases-risk-of-kidney-disease\/","title":{"rendered":"Gout Increases Risk of Kidney Disease"},"content":{"rendered":"

Previous research has indicated that gout may increase the risk of chronic kidney disease (CKD), but a new study has determined just how much greater the risk is.<\/span><\/p>\n

Conclusively linking gout to kidney failure<\/b><\/p>\n

In research published in <\/span>BMJ Open<\/span><\/i>, scientists looked at data from 68,897 adults with gout and 554,964 adults without gout. They followed both groups for 3.68 years, on average.<\/span><\/p>\n

The study used the following guidelines to define advanced kidney disease:<\/span><\/p>\n

The first occurrence of \u2026<\/span><\/p>\n

\u2026 kidney function at less than 10% of normal<\/span><\/p>\n

\u2026 dialysis, transplant or end-stage kidney disease<\/span><\/p>\n

\u2026 a doubling of serum creatinine from the baseline levels<\/span><\/p>\n

\u2026 death associated with CKD<\/span><\/p>\n

\u00a0<\/span>Even after controlling for factors like diabetes, heart disease, hypertension, smoking, alcohol use and drugs that impact kidney function, the correlation between gout and kidney disease was shocking.<\/span><\/p>\n

\u201cThe results were quite astonishing,\u201d says Professor Austin Stack from the University of Limerick. \u201cWe discovered that patients who suffered from gout had a 29% higher risk of advanced chronic kidney disease compared to those without gout.\u201d<\/span><\/p>\n

This was especially true for those with end stage kidney disease, which created a twofold higher risk for the link to gout.<\/span>\u00a0<\/span><\/p>\n

\u201cTaken together,\u201d says Stack, \u201cthe findings from this study suggest that gout is an independent risk factor for progression of CKD and kidney failure.\u201d<\/span><\/p>\n

Limitations to the study<\/b><\/p>\n

The study was large, but still had some limitations.<\/span>\u00a0<\/span><\/p>\n

First, gout was only assessed by looking at a doctor\u2019s diagnosis or by the participant registering their use of urate-lowering treatments. But gout often goes undiagnosed, making it possible that some people were not counted among those with gout, even though they had it.<\/span><\/p>\n

Also, the study was observational, so it\u2019s possible that there could be an unmeasured variable that would otherwise affect the results.<\/span>\u00a0<\/span><\/p>\n

Regardless, there\u2019s enough information to encourage doctors to get gout under control in hopes of reducing the risk of CKD progression.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Previous research has indicated that gout may increase the risk of chronic kidney disease (CKD), but a new study has determined just how much greater the risk is. Conclusively linking gout to kidney failure In research published in BMJ Open, scientists looked at data from 68,897 adults with gout and 554,964 adults without gout. They […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[711],"tags":[],"class_list":["post-14242","post","type-post","status-publish","format-standard","hentry","category-gout"],"_links":{"self":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts\/14242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/comments?post=14242"}],"version-history":[{"count":0,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts\/14242\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/media?parent=14242"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/categories?post=14242"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/tags?post=14242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}