{"id":14381,"date":"2019-10-14T19:32:52","date_gmt":"2019-10-14T19:32:52","guid":{"rendered":"https:\/\/www.healthymale.com\/squad\/?p=14381"},"modified":"2019-10-14T19:32:52","modified_gmt":"2019-10-14T19:32:52","slug":"diabetics-can-fight-atherosclerosis-with-cholesterol","status":"publish","type":"post","link":"https:\/\/www.healthymale.com\/blog\/diabetes\/diabetics-can-fight-atherosclerosis-with-cholesterol\/","title":{"rendered":"Diabetics Can Fight Atherosclerosis With Cholesterol"},"content":{"rendered":"

Although diabetics have a greater risk of developing atherosclerosis, a new study indicates that \u201cgood\u201d cholesterol may help fight it.<\/span><\/p>\n

Studying diabetes and atherosclerosis<\/b><\/p>\n

Scientists from New York University School of Medicine wanted to know if increasing HDL levels (also known as \u201cgood\u201d cholesterol) could help fight atherosclerosis in diabetics. They decided to focus on \u201cfunctional HDL,\u201d that is, the kind that promotes the extraction of cholesterol from cells.<\/span><\/p>\n

For the study, which used mice with diabetes and atherosclerosis, the researchers raised functional HDL levels by increasing the amounts of apoA-1 either through an injection into their bloodstream or by using mice that were genetically engineered to boost the production of apoA-1.<\/span>\u00a0<\/span><\/p>\n

Both groups of mice with increased functional HDL levels saw a boost in the reversal of atherosclerosis. In fact, it reduced inflammation in atherosclerotic plaques by half and blocked certain white blood cells called <\/span>neutrophils<\/span><\/i> from contributing to reduced blood flow in atherosclerosis.\u00a0 Mice who also received a treatment to lower \u201cbad\u201d cholesterol had an additional 30% boost in the reversal of atherosclerosis.<\/span>\u00a0<\/span><\/p>\n

\u201cFor the study, we built our own version of the HDL particle, called reconstituted HDL,\u201d says first author Tessa Barrett, Ph.D., \u201cwhich promises to become the basis for new kinds of functional HDL treatments that finally reduce the residual risk for cardiovascular disease not addressed currently.\u201d<\/span><\/p>\n

The research was published in the journal <\/span>Circulation.<\/span><\/i><\/p>\n

Why it matters to diabetics<\/b><\/p>\n

For many people with diabetes, health issues are already a major concern. But with an increased risk of developing hardened arteries, this new research could be a major breakthrough. The plaque buildup from atherosclerosis can lead to a heart attack or stroke.<\/span><\/p>\n

Although this was only a preclinical study, the investigative team hopes that the results may lead to more effective treatments for atherosclerosis down the road.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Although diabetics have a greater risk of developing atherosclerosis, a new study indicates that \u201cgood\u201d cholesterol may help fight it. Studying diabetes and atherosclerosis Scientists from New York University School of Medicine wanted to know if increasing HDL levels (also known as \u201cgood\u201d cholesterol) could help fight atherosclerosis in diabetics. They decided to focus on […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[753],"tags":[722,714],"class_list":["post-14381","post","type-post","status-publish","format-standard","hentry","category-diabetes","tag-cholesterol","tag-diabetes"],"_links":{"self":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts\/14381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/comments?post=14381"}],"version-history":[{"count":0,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts\/14381\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/media?parent=14381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/categories?post=14381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/tags?post=14381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}