{"id":14529,"date":"2019-11-18T20:14:01","date_gmt":"2019-11-18T20:14:01","guid":{"rendered":"https:\/\/www.healthymale.com\/squad\/?p=14529"},"modified":"2019-11-18T20:14:01","modified_gmt":"2019-11-18T20:14:01","slug":"anti-inflammatories-may-increase-diabetes-risk","status":"publish","type":"post","link":"https:\/\/www.healthymale.com\/blog\/diabetes\/anti-inflammatories-may-increase-diabetes-risk\/","title":{"rendered":"Anti-inflammatories May Increase Diabetes Risk"},"content":{"rendered":"<p><span style=\"font-weight: 400\">Anyone at risk for diabetes should take note: new research presented at The Society for Endocrinology Annual Conference found that anti-inflammatory drugs appear to increase the risk for diabetes.<\/span><\/p>\n<p><b>Studying anti-inflammatories and diabetes<\/b><\/p>\n<p><span style=\"font-weight: 400\">Teams of researchers from the University of Oxford and Sapienza University in Italy recruiting healthy male volunteers to take either 10 milligrams or 15 milligrams of prednisolone (glucocorticoids) for a week. These are the doses that doctors typically prescribe for things like arthritis, allergies or asthma.<\/span><\/p>\n<p><span style=\"font-weight: 400\">At the end of the treatment, the scientists measured metabolic markers and regular biomarkers (e.g., weight and fasting blood sugar) to see if anything had changed.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Although most of the biomarkers hadn\u2019t been affected by the anti-inflammatories, the researchers noted that the blood sugar regulation mechanisms seemed to have been negatively impacted. Over the long term, this could increase a person\u2019s risk for diabetes.<\/span><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u201cThis is the first study to examine the very short-term metabolic effects of commonly prescribed doses of glucocorticoids on healthy men and indicates that, even at these lower doses, glucose metabolism is impaired, suggested an increased risk of diabetes with continued treatment,\u201d says study author Dr. Riccardo Pofi. \u201cThis [research] suggests that we need to more accurately assess [glucocorticoid] use in patients to prevent and reduce the undesired effects, especially in patients for which steroid treatment is essential for life.\u201d<\/span><\/p>\n<p><b>Anti-inflammatory risks<\/b><\/p>\n<p><span style=\"font-weight: 400\">Glucocorticoids can come with other risks besides increasing your chances of developing diabetes. Potential side effects include sleep issues, shortness of breath and dry and\/or discolored skin.<\/span><\/p>\n<p><span style=\"font-weight: 400\">When taken at higher doses, some people report experiencing high blood pressure and depression.<\/span><\/p>\n<p><b>More research needed<\/b><\/p>\n<p><span style=\"font-weight: 400\">More research\u2014with a larger cohort\u2014needs to be done to confirm the validity of this research.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Dr. Pofi and his team want to investigate whether it\u2019s possible to prevent or at least reduce the metabolic impact of glucocorticoids.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anyone at risk for diabetes should take note: new research presented at The Society for Endocrinology Annual Conference found that anti-inflammatory drugs appear to increase the risk for diabetes. Studying anti-inflammatories and diabetes Teams of researchers from the University of Oxford and Sapienza University in Italy recruiting healthy male volunteers to take either 10 milligrams [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[753],"tags":[714],"class_list":["post-14529","post","type-post","status-publish","format-standard","hentry","category-diabetes","tag-diabetes"],"_links":{"self":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts\/14529","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/comments?post=14529"}],"version-history":[{"count":0,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/posts\/14529\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/media?parent=14529"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/categories?post=14529"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthymale.com\/blog\/wp-json\/wp\/v2\/tags?post=14529"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}