Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Hair Loss
Targeted approaches for every stage of androgenetic alopecia
Hair loss (androgenetic alopecia) affects over 80 million Americans, primarily driven by genetic sensitivity to DHT. Modern science provides targeted solutions at every stage of progression. This guide compares FDA-approved drugs, compounded topicals, and OTC/device-based options based on proven efficacy and safety profiles.
Genetic sensitivity determines progression speed. Early intervention is key to preserving existing follicles and slowing miniaturization.
| Medication | Formulation | Key Benefit | Best For |
|---|---|---|---|
| Finasteride | Oral tablet (1mg daily) | Reduces scalp DHT by 60–70% | Men with vertex/crown thinning |
| Dutasteride | Oral capsule (0.5mg daily) | Blocks 90%+ DHT (all 3 isoforms) | Men with aggressive loss |
| Propecia® | Branded finasteride | Same efficacy as generic | Patients preferring brand assurance |
Prescription Required: Not for premenopausal women. Reported side effects <2% (reversible upon discontinuation).
Custom solutions that deliver actives directly to follicles while minimizing systemic exposure.
| Product | Active Ingredients | Clinical Advantage |
|---|---|---|
| Mens Hair TriGro | Minoxidil 5% + Finasteride 0.1% + Tretinoin 0.01% | Combats DHT + enhances absorption |
| Womens Hair TriGro Ageless | Minoxidil 2% + Spironolactone 1% + Biotin 0.5% | Anti-androgen + follicle nutrition |
| Womens Hair TriGro Vibrant | Minoxidil 5% + Finasteride 0.025% + Melatonin 0.1% | Nighttime growth stimulation |
2024 JAMA Study: Topical finasteride reduced serum DHT by only 24% vs. 70% with oral therapy.
| Product | Key Actives | Mechanism |
|---|---|---|
| Minoxidil | 5% (men), 2–5% (women) | Vasodilator ? ? follicular nutrients |
| Hair Growth for Men | Caffeine + Adenosine | Blocks DHT binding + reduces inflammation |
| Hair Growth for Women | Capixyl™ + Redensyl | Stem cell activation + antioxidant support |
| Product | Technology | Clinical Protocol |
|---|---|---|
| Laser Hair Growth Comb | Low-level laser (650nm) | 10min, 3x/week (FDA-cleared) |
| Minoxidil Applicator Comb | Precision nozzle | Targets thinning zones |
Tip: Switch protocols at 6 months if no reduction in shedding is observed.
Seek Doctor evaluation for:
