A new study published in Nature Genetics has found 63 new genetic markers that might make it easier for doctors to determine if you have a greater risk of developing prostate cancer, as well as other diseases. Previously, about 100 genetic markers for prostate cancer had been identified.
The research on new genetic markers for prostate cancer
The study, which was conducted by a team at Case Westerns Reserve University School of Medicine, looked at the DNA sequences of approximately 140,000 men of European descent. This included data from previous studies as well. While 60,000 of the men had no signs of the disease, the other 80,000 or so had the cancer. The men with prostate cancer had 63 genetic markers that the cancer-free men didn’t have.
Researchers believe that there may be as many as 1,000 genetic markers linked to prostate cancer.
Early screenings for prostate cancer
These 63 new genetic markers will allow doctors to identify which men should have early and regular PSA screenings. The discovery may also help inform treatments at some point in the future.
A man’s genetic score may help doctors determine what type of treatment to use. For example, with a greater the number of genetic markers, a more aggressive treatment may be chosen to reduce the chances of the cancer returning.
PSAs measure the amount of protein in the blood. Men who receive a PSA result that is under 2.5 nanograms per milliliter may not need to be tested for the next two years, while those whose results are 2.5 nanograms or higher should be screened each year.
Prostate cancer in the United States
According to the National Cancer Institute, prostate cancer is the No. 1 most common cancer among men and the second leading cause of cancer death. About 60% of the cases are found in men over 65. Men with a family history of the disease are more likely to develop it.
